NAD+ 500mg – High Purity Research Grade Powder (UK Stocked)

 NAD+ (β-Nicotinamide Adenine Dinucleotide) 500mg – High Purity Lyophilised Research Powder

NAD+ (β-Nicotinamide adenine dinucleotide) is a critical coenzyme involved in essential biochemical processes across all living cells. Our NAD+ 500mg research-grade powder is a high-purity, HPLC-verified, lyophilised formulation, supplied strictly for laboratory research applications only.

Each batch is manufactured and handled under controlled conditions to ensure consistency, traceability, and analytical reliability for scientific studies.

What is NAD+ (Nicotinamide Adenine Dinucleotide)?

NAD+ is a naturally occurring coenzyme found in all living cells, where it plays a fundamental role in cellular energy metabolism and redox reactions.

It functions as a key electron carrier in the conversion of nutrients into cellular energy (ATP), acting within the NAD+/NADH redox cycle, which is essential for maintaining metabolic balance.

In biochemical research, NAD+ is widely studied for its involvement in:

• Cellular energy transfer mechanisms
• Oxidation-reduction (redox) reactions
• Enzymatic activity regulation
• Mitochondrial metabolic pathways

Due to its central role in metabolism, NAD+ is one of the most extensively studied coenzymes in molecular biology and biochemistry.

Scientific Role of NAD+ in Cellular Biology

NAD+ is not just a metabolic cofactor—it is a core regulator of cellular function.

Key biological roles include:

1. Energy Metabolism

NAD+ facilitates electron transfer in metabolic reactions, supporting ATP production through glycolysis and oxidative phosphorylation.

2. DNA Repair Mechanisms

NAD+ is consumed by enzymes such as PARPs (Poly ADP-ribose polymerases), which are involved in DNA repair and genomic stability maintenance.

3. Sirtuin Enzyme Activity

NAD+ acts as a required cofactor for sirtuin enzymes (SIRT1–SIRT7), which regulate gene expression, stress response, and metabolic efficiency.

4. Redox Homeostasis

It maintains cellular balance between oxidation and reduction states, essential for normal biochemical function.

NAD+ vs NADH vs NMN (Scientific Comparison)

Understanding NAD+ in context is important for biochemical research.

Compound	Function	Role in Research
NAD+	Oxidized coenzyme form	Central in redox reactions and metabolic pathways
NADH	Reduced form of NAD+	Electron donor in energy production
NMN	NAD+ precursor	Studied for NAD+ biosynthesis pathways

NAD+ and NADH operate as a biological pair in cellular respiration, while NMN is primarily investigated as a precursor in NAD+ biosynthesis pathways.

Research Applications

This NAD+ 500mg material is suitable for controlled laboratory use in biochemical and molecular research, including:

• Cellular metabolism studies
• Enzyme cofactor analysis
• Redox reaction research
• Mitochondrial function investigations
• NAD+/NADH cycle studies
• Sirtuin-related pathway research
• Biochemical energy transfer experiments

For laboratory research use only. Not intended for diagnostic, therapeutic, or human consumption.

Product Specifications

Parameter	Details
Compound	NAD+ (β-Nicotinamide Adenine Dinucleotide)
CAS Number	53-84-9
PubChem CID	5892
ChEMBL ID	ChEMBL1426
Molecular Formula	C₂₁H₂₇N₇O₁₄P₂
Molecular Weight	~663.43 g/mol
Content	500mg per vial
Form	Lyophilised (freeze-dried powder)
Purity	≥ 99% (HPLC verified)
Storage	Store at –20°C in a dry, controlled environment
Documentation	Certificate of Analysis (COA) included per batch
Origin	UK-stocked for rapid dispatch

Quality Assurance & Testing

Each batch of NAD+ undergoes strict analytical verification to ensure reproducibility and purity standards suitable for advanced research.

Quality control includes:

• High-Performance Liquid Chromatography (HPLC) purity testing
• Batch-specific analytical validation
• Controlled freeze-drying (lyophilisation) process
• Stability and contamination screening

A Certificate of Analysis (COA) is provided with every batch for full transparency and traceability.

Stability & Storage Information

NAD+ is a sensitive biomolecule that degrades under heat, moisture, and prolonged exposure to light.

To preserve integrity:

• Store at -20°C immediately upon receipt
• Keep in a dry, airtight container
• Avoid repeated freeze-thaw cycles
• Minimise exposure to humidity and ambient light

The lyophilised format enhances stability during storage and transport.

Regulatory Statement

This product is supplied strictly for laboratory research purposes only.

It is:

• Not intended for human consumption
• Not intended for diagnostic use
• Not intended for therapeutic or medical applications
• Not approved as a drug, supplement, or food product

Users are responsible for ensuring compliance with local research regulations.

Frequently Asked Questions (FAQ)

What is NAD+ used for in research?

NAD+ is used to study cellular energy metabolism, redox reactions, enzyme activity, and mitochondrial function.

Is NAD+ the same as NMN?

No. NAD+ is the active coenzyme, while NMN is a precursor involved in NAD+ biosynthesis pathways.

Why is NAD+ stored at -20°C?

NAD+ is temperature-sensitive and degrades under heat or moisture. Cold storage preserves molecular stability.

What does ≥99% purity mean?

It indicates that the compound has been verified via HPLC testing to contain at least 99% NAD+ with minimal impurities.

Is this NAD+ suitable for human use?

No. This product is strictly for laboratory research only and is not approved for human consumption.

What does CAS 53-84-9 represent?

This is the unique chemical identifier assigned to NAD+ for standardized global referencing.

Scientific References (Optional for Trust Building)

• PubChem: NAD+ Compound Profile (CID: 5892)
• NAD+/NADH redox biology literature (biochemistry journals)
• Sirtuin enzyme research studies in molecular metabolism journals

Short Product Summary (for Shopify/Kadence excerpt)

High-purity NAD+ (β-Nicotinamide adenine dinucleotide) 500mg lyophilised powder, ≥99% HPLC-verified, supplied with COA. Designed for biochemical and cellular research applications. UK-stocked with controlled -20°C storage handling. For laboratory research use only.