NAD+ (β-Nicotinamide Adenine Dinucleotide) 500mg – High Purity Lyophilised Research Powder

NAD+ (β-Nicotinamide adenine dinucleotide) is a critical coenzyme that supports essential biochemical processes across all living cells. Our NAD+ 500mg research-grade powder features a high-purity, HPLC-verified, lyophilised formulation designed exclusively for laboratory research applications. Furthermore, we manufacture and handle every batch under controlled conditions to ensure consistency, traceability, and analytical reliability for scientific studies.

What is NAD+ (Nicotinamide Adenine Dinucleotide)?

NAD+ is a naturally occurring coenzyme found in all living cells, where it plays a fundamental role in cellular energy metabolism and redox reactions. Additionally, it functions as a key electron carrier during the conversion of nutrients into cellular energy (ATP) through the NAD+/NADH redox cycle, helping maintain metabolic balance. Researchers also study NAD+ extensively for its involvement in:

• Cellular energy transfer mechanisms
• Oxidation-reduction (redox) reactions
• Enzymatic activity regulation
• Mitochondrial metabolic pathways

Consequently, NAD+ remains one of the most extensively researched coenzymes in molecular biology and biochemistry because of its central role in cellular metabolism.

Scientific Role of NAD+ in Cellular Biology

NAD+ is more than a metabolic cofactor. Instead, it serves as a central regulator of numerous cellular processes.

1. Energy Metabolism

NAD+ facilitates electron transfer during metabolic reactions, thereby supporting ATP production through glycolysis and oxidative phosphorylation.

2. DNA Repair Mechanisms

Enzymes such as PARPs (Poly ADP-ribose polymerases) consume NAD+ during DNA repair and genomic stability processes.

3. Sirtuin Enzyme Activity

Moreover, NAD+ acts as an essential cofactor for sirtuin enzymes (SIRT1-SIRT7), helping regulate gene expression, stress responses, and metabolic efficiency.

4. Redox Homeostasis

Finally, NAD+ helps maintain the balance between oxidation and reduction, supporting normal biochemical function.

NAD+ vs NADH vs NMN (Scientific Comparison)

Understanding the relationship between these molecules provides important context for biochemical research.

Compound	Function	Role in Research
NAD+	Oxidized coenzyme form	Central to redox reactions and metabolic pathways
NADH	Reduced form of NAD+	Electron donor in cellular energy production
NMN	NAD+ precursor	Studied in NAD+ biosynthesis pathways

NAD+ and NADH function together as a biological redox pair during cellular respiration. Meanwhile, researchers investigate NMN primarily for its role as a precursor in NAD+ biosynthesis.

Research Applications

Researchers use this NAD+ 500mg material in controlled biochemical and molecular laboratory studies, including:

• Cellular metabolism studies
• Enzyme cofactor analysis
• Redox reaction research
• Mitochondrial function investigations
• NAD+/NADH cycle studies
• Sirtuin-related pathway research
• Biochemical energy transfer experiments

This product is intended strictly for laboratory research and is not suitable for diagnostic, therapeutic, or human use.

---

Product Specifications

Parameter	Details
Compound	NAD+ (β-Nicotinamide Adenine Dinucleotide)
CAS Number	53-84-9
PubChem CID	5892
ChEMBL ID	ChEMBL1426
Molecular Formula	C₂₁H₂₇N₇O₁₄P₂
Molecular Weight	~663.43 g/mol
Content	500mg per vial
Form	Lyophilised (freeze-dried powder)
Purity	≥99% (HPLC verified)
Storage	Store at –20°C in a dry, controlled environment
Documentation	Certificate of Analysis (COA) included with every batch
Origin	UK-stocked for rapid dispatch

Quality Assurance & Testing

Furthermore, our quality control team verifies every batch of NAD+ through strict analytical testing to ensure reproducibility and high-purity standards for advanced research. Quality control includes:

• High-Performance Liquid Chromatography (HPLC) purity testing
• Batch-specific analytical validation
• Controlled freeze-drying (lyophilisation)
• Stability and contamination screening

Additionally, we include a Certificate of Analysis (COA) with every batch to provide complete transparency and traceability.

Stability & Storage Information

NAD+ is a sensitive biomolecule that degrades when exposed to heat, moisture, and prolonged light. To preserve product integrity:

• Store at –20°C immediately upon receipt.
• Keep the vial in a dry, airtight container.
• Avoid repeated freeze-thaw cycles.
• Minimise exposure to humidity and ambient light.

Moreover, the lyophilised format improves stability during storage and transport.

Regulatory Statement

We supply this product exclusively for laboratory research purposes. It is:

• Not intended for human consumption
• Not intended for diagnostic use
• Not intended for therapeutic or medical applications
• Not approved as a drug, supplement, or food product

Therefore, users are responsible for ensuring compliance with all applicable laboratory regulations and research guidelines.

Frequently Asked Questions (FAQ)

What is NAD+ used for in research?

Researchers use NAD+ to investigate cellular energy metabolism, redox reactions, enzyme activity, mitochondrial function, and related biochemical pathways.

Is NAD+ the same as NMN?

No. NAD+ is the active coenzyme, whereas NMN serves as a precursor in NAD+ biosynthesis.

Why should NAD+ be stored at –20°C?

Cold storage helps preserve molecular stability because NAD+ is sensitive to heat and moisture.

What does ≥99% purity mean?

HPLC testing confirms that the material contains at least 99% NAD+ with minimal impurities.

Is this NAD+ suitable for human use?

No. This product is strictly for laboratory research only and is not approved for human or veterinary use.

What does CAS 53-84-9 represent?

CAS 53-84-9 is the internationally recognised Chemical Abstracts Service identifier assigned to NAD+.

Scientific References

• PubChem: NAD+ Compound Profile (CID: 5892)
• NAD+/NADH redox biology literature
• Peer-reviewed molecular metabolism and sirtuin research publications

Short Product Summary

High-purity NAD+ (β-Nicotinamide adenine dinucleotide) 500mg lyophilised research powder with ≥99% HPLC-verified purity and a Certificate of Analysis (COA). Designed for biochemical, molecular biology, and cellular metabolism research. UK-stocked for rapid dispatch. For laboratory research use only.